Searchable abstracts of presentations at key conferences in endocrinology

ea0085p83 | Pituitary and Growth 2 | BSPED2022

DNA haplotypes influencing the response to growth hormone therapy are disproportionately inherited from neanderthals

Murray Philip , Hussain Asad , Garner Terence , Stevens Adam

Background: Neanderthals split from an ancestral human population ~500,000 years ago and lived in Eurasia until 40,000 years ago. Early modern humans emerged in Africa ~350,000 years ago migrating into Eurasia 50,000 years ago. Interbreeding occurred between early modern humans and Neanderthals leading to the introduction of Neanderthal DNA into the early human population, a process termed introgression. In modern Eurasian populations around 2-4% of DNA is of Neanderthal origi...